Autosomal dominant juvenile onset glaucoma affecting six generations in an Edinburgh family

Autosomal dominant juvenile onset glaucoma affecting six generations in an Edinburgh family.

Hereditary Glaucoma Occurrence in Five Generations of an Edinburgh Family.

A REGULAR Mendelian dominant pattern of inheritance is characteristic of so-called juvenile glaucoma and some hundred genealogies have been recorded (Fran9ois, 1961), two-thirds showing one or two affected generations and the other third three to six generations. However, in a condition of such high prevalence as primary glaucoma, two successive affected generations are not sufficient to prove ...

Hereditary Glaucoma Affecting Three Generations

the ages of 50 and 60. Sindan Kia Khan had been to Col. H. Smith of Amritsar for operation and apparently an iridectomy had been done but with no improvement. I took a photograph* of the three brothers, the three old men standing behind and two of their sons sitting in front, and told them that if any of the third generation were affected to let me know at once. This year 1 discovered that a fo...

Autosomal dominant juvenile recurrent parotitis.

Juvenile recurrent parotitis is a common cause of inflammatory salivary gland swelling in children. A variety of aetiological factors has been proposed for the condition. Here we present a family where four members had juvenile recurrent parotitis and where two other family members may have had an atypical form of the condition. The segregation pattern in the family is consistent with autosomal...

A genome-wide scan maps a novel autosomal dominant juvenile-onset open-angle glaucoma locus to 2p15-16

PURPOSE To study the clinical features and to perform genetic linkage study in two large Chinese families with autosomal dominant juvenile-onset primary open-angle glaucoma (POAG). METHODS Eighteen members of one Chinese family and 25 members of a second Chinese family with juvenile-onset primary open-angle glaucoma (POAG) were investigated. Thirteen members in one family and 14 members in th...